Total Parenteral Nutrition

Total Parenteral Nutrition
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Total parenteral nutrition (TPN), is the practice of feeding a person intravenously, bypassing the usual process of eating and digestion. The person receives nutritional formulas containing salts, glucose, amino acids, lipids and added vitamins.

General Usage TPN is normally used following surgery, when feeding by mouth or using the gut is not possible, when a person's digestive system cannot absorb nutrients due to chronic (medicine), or, alternatively, if a person's nutrient requirement cannot be met by enteral feeding (tube feeding) and supplementation. It has been used for Coma patients, although enteral feeding is usually preferable, and less prone to complications. Short-term TPN may be used if a person's digestive system has shut down (for instance by Peritonitis), and they are at a low enough weight to cause concerns about nutrition during an extended hospital stay. Long-term TPN is occasionally used to treat people suffering the extended consequences of an accident or surgery. Most controversially, TPN has extended the life of a small number of children born with nonexistent or severely birth-deformed guts. The oldest were eight years old in 2003.

The preferred method of delivering TPN is with a medical infusion pump. A sterilization (microbiology) bag of nutrient solution, between 500 mL and 4 L is provided. The pump infuses a small amount (0.1 to 10 mL/hr) continuously in order to keep the vein open. Feeding schedules vary, but one common regimen ramps up the nutrition over a few hours, levels off the rate for a few hours, and then ramps it down over a few more hours, in order to simulate a normal set of meal times.

The nutrient solution consists of water, glucose, salts, amino acids, vitamins and (more controversially) sometimes emulsified fats. Long term TPN patients sometimes suffer from lack of trace nutrients or electrolyte imbalances. Because increased blood sugar commonly occurs with TPN, insulin may also be added to the infusion. Often though, an insignificant amount of insulin is added, sometimes 10 units or less in 2 liters of TPN. In actuality, the patient will probably get less than that. Occasionally, other drugs are added as well, sometimes unnecessarily.

Chronic TPN is performed through a central intravenous catheter, usually in the subclavian or jugular vein. Another common practice is to use a PICC line, which originates in the arm, and exends to one of the central veins, such as the subclavian. In infants, sometimes the umbilical vein is used.

Battery-powered ambulatory infusion pumps can be used with chronic TPN patients. Usually the pump and a small (100 ml) bag of nutrient (to keep the vein open) are carried in a small bag around the waist or on the shoulder. Outpatient TPN practices are still being refined.

Aside from their dependence on a pump, chronic TPN patients live quite normal lives.

Complications The most common complication of TPN use is bacterial infection, usually due to the increased infection risk from having an indwelling central venous catheter. Liver Liver failure may sometimes occur; a recent study at Children's Hospital Boston on the cause suggests it is due to a large difference in omega-6 to omega-3 ratio. When treated with Omegaven, a different fatty acid infusion (which is approved for limited use in the U.S.), two patients were able to recover from their condition.

Total parenteral nutrition - Wikipedia, the free encyclopedia
Total parenteral nutrition (TPN), is the practice of feeding a person intravenously, bypassing the usual process of eating and digestion. The person receives nutritional formulas ...

Definition: total parenteral nutrition from Online Medical Dictionary
The Online Medical Dictionary is a searchable dictionary of definitions from medicine, science and technology.

MedlinePlus Drug Information: Total Parenteral Nutrition
Total Parenteral Nutrition ... About your treatment Return to top. Your doctor has ordered total parenteral nutrition (TPN) for you.

Total Parenteral Nutrition - Bliss
Total Parenteral Nutrition - Bliss ... Total Parenteral Nutrition also know as TPN is used for extremely premature infants or very sick newborn infants.

Total parenteral nutrition
Total parenteral nutrition What is total parenteral nutrition? "Parenteral" means administered any other way except by the mouth. "Nutrition" means feeding.

NHSGGC / Nutrition/Total Parenteral Nutrition
Parenteral nutrition provides means of nutrition for patients who are unable to eat, and who cannot be treated with enteral nutrition. It needs to be kept in mind that it is an ...

Studies on the regulation of food intake using rat total parenteral ...
Studies on the regulation of food intake using rat total parenteral nutrition as a model

Total Parenteral Nutrition
Samuel Chan George L. Blackburn Nutrition Support Service Department of Surgery Beth Israel Deaconess Medical Center/Harvard Medical School Boston, Massachusetts

Total Parenteral Nutrition
Total Parenteral Nutrition. Other Names: TPN About your treatment. Your doctor has ordered total parenteral nutrition (TPN) for you. TPN will drip through a needle or catheter ...

total parenteral nutrition - Hutchinson encyclopedia article about ...
nutrition. Strategy adopted by an organism to obtain the chemicals it needs to live, grow, and reproduce. These chemicals are nutrients that are absorbed from the environment, such ...





 
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